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Annals of Clinical Biochemistry

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Ann Clin Biochem 2008;45:539-559
doi:10.1258/acb.2008.008039
© 2008 Association for Clinical Biochemistry

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Circulating markers for endocrine tumours of the gastroenteropancreatic tract

Joy E S Ardill


Regional Regulatory Peptide Laboratory, Department of Clinical Biochemistry, Royal Victoria Hospital and Queen's University, Belfast BT12 6BJ, UK


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  		Figure 1 The sequences of various peptides secreted by neuroendocrine tumours illustrating structural similarities and differences. *Pro-insulin is folded to show the insulin sequence in bold, comprising A and B chains. CGRP1, calcitonin gene-related peptide 1; CGRP2, calcitonin gene-related peptide 2; G17, gastrin 17; G34, gastrin 34; GLP1, pro-glucagon 77–107; GLP2, pro-glucagon 126–258; NKA, neurokinin A; NKB, neurokinin B; NPY, neuropeptide Y; pancreatic glucagon, pro-glucagon 1–29; PP, pancreatic polypeptide; PYY, peptide Y, S14, somatostatin 14; S28, somatostatin 28; SP, substance P

 

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