Personal View

Callum G Fraser

Faecal occult blood tests – eliminate, enhance or update?
Ann Clin Biochem 45(2): 117-121; doi:10.1258/acb.2008.007223 [Abstract] [Full Text] [PDF]  

Review Article

Gordon Ferns and Vuyolethu Keti

HDL-cholesterol modulation and its impact on the management of cardiovascular risk
Ann Clin Biochem 45(2): 122-128; doi:10.1258/acb.2007.007177 [Abstract] [Full Text] [Figures Only] [PDF]  

Original Article

Maurice J O'Kane, P L Mark Lynch, and Noel McGowan

The development of a system for the reporting, classification and grading of quality failures in the clinical biochemistry laboratory
Ann Clin Biochem 45(2): 129-134; doi:10.1258/acb.2007.007097 [Abstract] [Full Text] [Figures Only] [PDF]  

David Housley, Edward Kearney, Emma English, Natalie Smith, Teresa Teal, Janina Mazurkiewicz, and Danielle B Freedman

Audit of internal quality control practice and processes in the south-east of England and suggested regional standards
Ann Clin Biochem 45(2): 135-139; doi:10.1258/acb.2007.007028 [Abstract] [Full Text] [Figures Only] [PDF]  

Bendix Carstensen, J Lindström, J Sundvall, K Borch-Johnsen, J Tuomilehto the DPS Study Group

Measurement of blood glucose: comparison between different types of specimens
Ann Clin Biochem 45(2): 140-148; doi:10.1258/acb.2007.006212 [Abstract] [Full Text] [Figures Only] [PDF]  

Heather Perry and Brian Keevil

Online extraction of 5-hydroxyindole acetic acid from urine for analysis by liquid chromatography–tandem mass spectrometry
Ann Clin Biochem 45(2): 149-152; doi:10.1258/acb.2007.007067 [Abstract] [Full Text] [Figures Only] [PDF]  

Heinz Jürgen Roth, Heinrich Schmidt-Gayk, Holger Weber, and Christoph Niederau

Accuracy and clinical implications of seven 25-hydroxyvitamin D methods compared with liquid chromatography–tandem mass spectrometry as a reference
Ann Clin Biochem 45(2): 153-159; doi:10.1258/acb.2007.007091 [Abstract] [Full Text] [Figures Only] [PDF]  

Romina P Barbagallo, Nick Boley, Gill Holcombe, Sheila Merson, Chris Mussell, Caroline Pritchard, Peter Stokes, Steve Wood, David Ducroq, and Annette Thomas

Production and certification of four frozen human serum certified reference materials containing creatinine and electrolytes
Ann Clin Biochem 45(2): 160-166; doi:10.1258/acb.2007.007126 [Abstract] [Full Text] [Figures Only] [PDF]  

T Ankrah-Tetteh, S Wijeratne, and R Swaminathan

Intraindividual variation in serum thyroid hormones, parathyroid hormone and insulin-like growth factor-1
Ann Clin Biochem 45(2): 167-169; doi:10.1258/acb.2007.007103 [Abstract] [Full Text] [Figures Only] [PDF]  

Khemanganee E Liyanage, Amanda J Hooper, Joep C Defesche, John R Burnett, and Frank M van Bockxmeer

High-resolution melting analysis for detection of familial ligand-defective apolipoprotein B-100 mutations
Ann Clin Biochem 45(2): 170-176; doi:10.1258/acb.2007.007077 [Abstract] [Full Text] [Figures Only] [PDF]  

Daniel Juan Herrera, Kevin Morris, Chris Johnston, and Paul Griffiths

Automated assay for plasma D-lactate by enzymatic spectrophotometric analysis with sample blank correction
Ann Clin Biochem 45(2): 177-183; doi:10.1258/acb.2007.007088 [Abstract] [Full Text] [Figures Only] [PDF]  

Paul O Collinson, Gloria H Gaynor, and David C Gaze

Cardiac troponin I measurement using the ACS:180 to predict four-year cardiac event rate
Ann Clin Biochem 45(2): 184-188; doi:10.1258/acb.2007.007050 [Abstract] [Full Text] [Figures Only] [PDF]  

Ian D Watson, Robert Beetham, Michael N Fahie-Wilson, Ian B Holbrook, and Daniel M O'Connell

What is the role of cerebrospinal fluid ferritin in the diagnosis of subarachnoid haemorrhage in computed tomography-negative patients?
Ann Clin Biochem 45(2): 189-192; doi:10.1258/acb.2007.007043 [Abstract] [Full Text] [Figures Only] [PDF]  

Mohsen Kerkeni, Faouzi Added, Mohamed Ben Farhat, Abdelhedi Miled, François Trivin, and Khira Maaroufi

Hyperhomocysteinaemia and parameters of antioxidative defence in Tunisian patients with coronary heart disease
Ann Clin Biochem 45(2): 193-198; doi:10.1258/acb.2007.007066 [Abstract] [Full Text] [Figures Only] [PDF]  

S G Hadfield, S Horara, B J Starr, S Yazdgerdi, D Bhatnagar, R Cramb, S Egan, R Everdell, G Ferns, A Jones, C B Marenah, J Marples, P Prinsloo, A Sneyd, M F Stewart, L Sandle, T Wang, M S Watson, and S E Humphries

Are patients with familial hypercholesterolaemia well managed in lipid clinics? An audit of eleven clinics from the Department of Health Familial Hypercholesterolaemia Cascade Testing project
Ann Clin Biochem 45(2): 199-205; doi:10.1258/acb.2007.007078 [Abstract] [Full Text] [Figures Only] [PDF]  

Short Report

F M Finucane, L Teong, S Pittock, M Fallon, M Hatunic, C Costigan, N Murphy, V E F Crowley, and J J Nolan

Adverse metabolic profiles in a cohort of obese Irish children
Ann Clin Biochem 45(2): 206-209; doi:10.1258/acb.2007.007115 [Abstract] [Full Text] [PDF]  

K Duxbury, L Owen, S Gillingwater, and B Keevil

Naturally occurring isotopes of an analyte can interfere with doubly deuterated internal standard measurement
Ann Clin Biochem 45(2): 210-212; doi:10.1258/acb.2007.007137 [Abstract] [Full Text] [Figures Only] [PDF]  

Ubaldo Pozzetto, Damiano Abeni, Franco Citterio, Marco Castagneto, Maurizio C Capogrossi, and Antonio Facchiano

Balance of transforming growth factor-β1 and platelet-derived growth factor-BB is associated with kidney allograft rejection
Ann Clin Biochem 45(2): 213-214; doi:10.1258/acb.2007.007155 [Abstract] [Full Text] [PDF]  

Case Report

T F J King, P O Shea, E P O Sullivan, R Srinivasan, A Griffin, R Fitzgerald, W Tormey, and D Smith

An apparent phaeochromocytoma and abnormal thyroid function tests
Ann Clin Biochem 45(2): 215-217; doi:10.1258/acb.2007.007106 [Abstract] [Full Text] [PDF]  

Francesco Vendrame, Antonella Verrienti, Claudio Parlapiano, Sebastiano Filetti, Francesco Dotta, and Susanna Morano

Thyrotoxic periodic paralysis in an Italian man: clinical manifestation and genetic analysis
Ann Clin Biochem 45(2): 218-220; doi:10.1258/acb.2007.007117 [Abstract] [Full Text] [Figures Only] [PDF]  

D M Comer, A G Droogan, I S Young, and A P Maxwell

Hypokalaemic paralysis precipitated by distal renal tubular acidosis secondary to Sjögren's syndrome
Ann Clin Biochem 45(2): 221-225; doi:10.1258/acb.2007.006080 [Abstract] [Full Text] [Figures Only] [PDF]  

Letter

Ruggero Dittadi, Lucia Peloso, and Massimo Gion

Within-subject biological variation in disease: the case of tumour markers
Ann Clin Biochem 45(2): 226-227; doi:10.1258/acb.2007.072441 [Full Text] [Figures Only] [PDF]  

Carmen Ricos

Author's response
Ann Clin Biochem 45(2): 227; doi:10.1258/acb.2007.072442 [Full Text] [PDF]  

Erratum

Guidelines for the investigation and management of a reduced level of consciousness in children: implication for clinical biochemistry laboratories
Ann Clin Biochem 45(2): 227-228; doi:10.1258/acb.2008.200812 [Full Text] [PDF]  

Books

Keith Griffiths

Evidence-Based Laboratory Medicine: Principles, Practice, and Outcomes (2nd edn)
Ann Clin Biochem 45(2): 229; doi:10.1258/acb.2008.200805 [Full Text] [PDF]  

Michael Norman

Culture of Human Stem Cells
Ann Clin Biochem 45(2): 229-230; doi:10.1258/acb.2008.200806 [Full Text] [PDF]  

Journal Watch

Anna L Barton

Anti-Müllerian hormone: a new marker for ovarian function
Ann Clin Biochem 45(2): 231; doi:10.1258/acb.2008.200804 [Full Text] [PDF]  

Michael S Crane

Classification and prediction of clinical Alzheimer's diagnosis based on plasma signalling proteins
Ann Clin Biochem 45(2): 231-232; doi:10.1258/acb.2008.200809 [Full Text] [PDF]  

Piscator

Ann Clin Biochem 45(2): 232; doi:10.1258/acb.2008.200813 [Full Text] [PDF]  

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