Editorial

Michael Fahie-Wilson and David Halsall

Polyethylene glycol precipitation: proceed with care
Ann Clin Biochem 45(3): 233-235; doi:10.1258/acb.2008.007262 [Full Text] [PDF]  

Guidelines

Anne M Cruickshank

Revision of national guidelines for cerebrospinal fluid analysis in suspected subarachnoid haemorrhage
Ann Clin Biochem 45(3): 236-237; doi:10.1258/acb.2008.007256 [Full Text] [PDF]  

Anne Cruickshank, Peter Auld, Robert Beetham, Gillian Burrows, William Egner, Ian Holbrook, Geoff Keir, Emma Lewis, Dina Patel, Ian Watson, and Peter White

Revised national guidelines for analysis of cerebrospinal fluid for bilirubin in suspected subarachnoid haemorrhage
Ann Clin Biochem 45(3): 238-244; doi:10.1258/acb.2008.007257 [Abstract] [Full Text] [Figures Only] [PDF]  

Review Article

Vivion E F Crowley

Overview of human obesity and central mechanisms regulating energy homeostasis
Ann Clin Biochem 45(3): 245-255; doi:10.1258/acb.2007.007193 [Abstract] [Full Text] [Figures Only] [PDF]  

Original Articles

Sweta Ram, Beverley Harris, Joseph J R Fernando, Rousseau Gama, and Michael Fahie-Wilson

False-positive polyethylene glycol precipitation tests for macroprolactin due to increased serum globulins
Ann Clin Biochem 45(3): 256-259; doi:10.1258/acb.2008.007233 [Abstract] [Full Text] [Figures Only] [PDF]  

Robert Cramb, Jane French, Michael Mackness, R Dermot G Neely, Muriel Caslake, and Finlay MacKenzie

Lipid external quality assessment: commutability between external quality assessment and clinical specimens
Ann Clin Biochem 45(3): 260-265; doi:10.1258/acb.2007.007120 [Abstract] [Full Text] [Figures Only] [PDF]  

Ian R Bailey and Vanessa R Thurlow

Is suboptimal phlebotomy technique impacting on potassium results for primary care?
Ann Clin Biochem 45(3): 266-269; doi:10.1258/acb.2007.007123 [Abstract] [Full Text] [Figures Only] [PDF]  

Daniëlle Berty Petra Eekers, Andrea Laschet, Monique de Groot, Erik Roelofs, Arnold Kester, Karl Delaere, Philippe Lambin, Francis van Gils, Marius Nap, and Joop ten Kate

Why determine only the total prostate-specific antigen, if the free-to-total ratio contains the information?
Ann Clin Biochem 45(3): 270-274; doi:10.1258/acb.2007.007014 [Abstract] [Full Text] [Figures Only] [PDF]  

Jillian R Tate, Wendy Ferguson, Renze Bais, Karam Kostner, Thomas Marwick, and Andrew Carter

The determination of the 99th centile level for troponin assays in an Australian reference population
Ann Clin Biochem 45(3): 275-288; doi:10.1258/acb.2007.007185 [Abstract] [Full Text] [Figures Only] [PDF]  

Denise Darby and Christopher Broomhead

Interference with serum indices measurement, but not chemical analysis, on the Roche Modular by Patent Blue V
Ann Clin Biochem 45(3): 289-292; doi:10.1258/acb.2007.007176 [Abstract] [Full Text] [Figures Only] [PDF]  

Catharina F M Linssen, Otto Bekers, Marjolein Drent, and Jan A Jacobs

C-reactive protein and procalcitonin concentrations in bronchoalveolar lavage fluid as a predictor of ventilator-associated pneumonia
Ann Clin Biochem 45(3): 293-298; doi:10.1258/acb.2007.007133 [Abstract] [Full Text] [PDF]  

Mohd Izani Othman, M I A Majid, Manjit Singh, Che Nin Man, and Gam Lay-Harn

Isolation, identification and quantification of differentially expressed proteins from cancerous and normal breast tissues
Ann Clin Biochem 45(3): 299-306; doi:10.1258/acb.2007.007104 [Abstract] [Full Text] [Figures Only] [PDF]  

Noriko Mukai, Toyofumi Nakanishi, Akira Shimizu, Takayuki Takubo, and Tsunehiko Ikeda

Identification of phosphotyrosyl proteins in vitreous humours of patients with vitreoretinal diseases by sodium dodecyl sulphate–polyacrylamide gel electrophoresis/Western blotting/matrix-assisted laser desorption time-of-flight mass spectrometry
Ann Clin Biochem 45(3): 307-312; doi:10.1258/acb.2007.007151 [Abstract] [Full Text] [Figures Only] [PDF]  

Short Reports

Kazuhiko Kotani, Naoki Sakane, Youichi Kurozawa, Akihiko Kaetsu, Mikizo Okamoto, Yoneatsu Osaki, and Takuji Kishimoto

Polymorphism of Trp64Arg in β₃-adrenergic receptor gene and serum LDL-cholesterol concentrations in healthy Japanese
Ann Clin Biochem 45(3): 313-315; doi:10.1258/acb.2007.007194 [Abstract] [Full Text] [PDF]  

Daan van de Kerkhof, Berry Peters, and Volkher Scharnhorst

Performance of the Advia Centaur second-generation troponin assay TnI-Ultra compared with the first-generation cTnI assay
Ann Clin Biochem 45(3): 316-317; doi:10.1258/acb.2007.007209 [Abstract] [Full Text] [Figures Only] [PDF]  

B Cauliez, J Guignery, S Marinier, I Mariau, and A Lavoinne

Two-year stability of NT-proBNP in frozen samples using the Roche Elecsys system
Ann Clin Biochem 45(3): 318-319; doi:10.1258/acb.2007.007187 [Abstract] [Full Text] [Figures Only] [PDF]  

Case Reports

J Cabrera-Abreu, R Jain, P Robinson, S Edees, and T Staughton

A case of aspartate aminotransferase macroenzyme
Ann Clin Biochem 45(3): 320-322; doi:10.1258/acb.2007.007063 [Abstract] [Full Text] [PDF]  

Robert Lord, Michael Fahie-Wilson, and Sanjay Suri

A paediatric case of macro aspartate aminotransferase
Ann Clin Biochem 45(3): 323-324; doi:10.1258/acb.2007.007094 [Abstract] [Full Text] [Figures Only] [PDF]  

V R Jahagirdar, P Strouhal, G Holder, R Gama, and B M Singh

Thyrotoxicosis factitia masquerading as recurrent Graves' disease: endogenous antibody immunoassay interference, a pitfall for the unwary
Ann Clin Biochem 45(3): 325-327; doi:10.1258/acb.2007.007163 [Abstract] [Full Text] [PDF]  

Sian Hancock, Rachel A Still, Andrew M Fielding, John F Doran, and Jeffrey W Stephens

A rare cause of Cushing's syndrome demonstrates analytical discrepancies between the Roche E170 and Bayer Centaur testosterone assays
Ann Clin Biochem 45(3): 328-330; doi:10.1258/acb.2007.007166 [Abstract] [Full Text] [PDF]  

Shweta Mehta and Tim Wang

Intermittent ovarian and thyroid failure and spontaneous twin pregnancy
Ann Clin Biochem 45(3): 331-334; doi:10.1258/acb.2007.007170 [Abstract] [Full Text] [Figures Only] [PDF]  

L Ranganath, W Taylor, L John, and Z Alfirevic

Biochemical diagnosis of placental infarction/damage: acutely rising alkaline phosphatase
Ann Clin Biochem 45(3): 335-338; doi:10.1258/acb.2007.007098 [Abstract] [Full Text] [Figures Only] [PDF]  

Letter

Shirley Twigger, Elizabeth Fox, and Keith Allen

Measurement of buprenorphine in urine: immunoassay versus LC-MS/MS
Ann Clin Biochem 45(3): 339; doi:10.1258/acb.2008.007250 [Full Text] [PDF]  

Books

Richard C Wilson

Nutrition and Laboratory Medicine
Ann Clin Biochem 45(3): 340; doi:10.1258/acb.2008.200807 [Full Text] [PDF]  

End Pieces

   Journal Watch

Neil Squires

Detection of prostate cancer in unselected young men: prospective cohort nested within a randomized controlled trial
Ann Clin Biochem 45(3): 341; doi:10.1258/acb.2008.200810 [Full Text] [PDF]  

   Piscator

Ann Clin Biochem 45(3): 342; doi:10.1258/acb.2008.200816 [Full Text] [PDF]  

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