Consensus Report

Julian H Barth, Sally M Marshall, and Ian D Watson

Consensus meeting on reporting glycated haemoglobin and estimated average glucose in the UK: report to the National Director for Diabetes, Department of Health
Ann Clin Biochem 45(4): 343-344; doi:10.1258/acb.2008.200815 [Full Text] [PDF]  

Personal View

Stuart J Moat

Plasma total homocysteine: instigator or indicator of cardiovascular disease?
Ann Clin Biochem 45(4): 345-348; doi:10.1258/acb.2008.008053 [Abstract] [Full Text] [PDF]  

Review Article

David C Gaze and Paul O Collinson

Multiple molecular forms of circulating cardiac troponin: analytical and clinical significance
Ann Clin Biochem 45(4): 349-355; doi:10.1258/acb.2007.007229 [Abstract] [Full Text] [Figures Only] [PDF]  

Original Articles

Ryunosuke Ohkawa, Kazuhiro Nakamura, Shigeo Okubo, Shigemi Hosogaya, Yukio Ozaki, Minoru Tozuka, Noriko Osima, Hiromitsu Yokota, Hitoshi Ikeda, and Yutaka Yatomi

Plasma sphingosine-1-phosphate measurement in healthy subjects: close correlation with red blood cell parameters
Ann Clin Biochem 45(4): 356-363; doi:10.1258/acb.2007.007189 [Abstract] [Full Text] [Figures Only] [PDF]  

Shigemi Hosogaya, Yutaka Yatomi, Kazuhiro Nakamura, Ryunosuke Ohkawa, Shigeo Okubo, Hiromitsu Yokota, Masato Ohta, Hirokazu Yamazaki, Toru Koike, and Yukio Ozaki

Measurement of plasma lysophosphatidic acid concentration in healthy subjects: strong correlation with lysophospholipase D activity
Ann Clin Biochem 45(4): 364-368; doi:10.1258/acb.2008.007242 [Abstract] [Full Text] [Figures Only] [PDF]  

Emel Sahin, Ayse Yesim Göçmen, Hüseyin Koçak, Murat Tuncer, and Saadet Gümüslü

The association of advanced glycation end-products with glutathione status
Ann Clin Biochem 45(4): 369-374; doi:10.1258/acb.2007.007186 [Abstract] [Full Text] [PDF]  

Melissa Tanner, Neil Kent, Brian Smith, Stephen Fletcher, and Michelle Lewer

Stability of common biochemical analytes in serum gel tubes subjected to various storage temperatures and times pre-centrifugation
Ann Clin Biochem 45(4): 375-379; doi:10.1258/acb.2007.007183 [Abstract] [Full Text] [PDF]  

Lisa Wood, David H Ducroq, Helen L Fraser, Scott Gillingwater, Carol Evans, Alan J Pickett, Derek W Rees, Rhys John, and Atilla Turkes

Measurement of urinary free cortisol by tandem mass spectrometry and comparison with results obtained by gas chromatography-mass spectrometry and two commercial immunoassays
Ann Clin Biochem 45(4): 380-388; doi:10.1258/acb.2007.007119 [Abstract] [Full Text] [Figures Only] [PDF]  

Etienne C H J Michielsen, Jaap A Bakker, Roland R J Van Kimmenade, Yigal M Pinto, and Marja P Van Dieijen-Visser

The diagnostic value of serum and urinary NT-proBNP for heart failure
Ann Clin Biochem 45(4): 389-394; doi:10.1258/acb.2007.007069 [Abstract] [Full Text] [Figures Only] [PDF]  

J C L Mamo, L Jian, A P James, L Flicker, H Esselmann, and J Wiltfang

Plasma lipoprotein β-amyloid in subjects with Alzheimer's disease or mild cognitive impairment
Ann Clin Biochem 45(4): 395-403; doi:10.1258/acb.2008.007214 [Abstract] [Full Text] [Figures Only] [PDF]  

Geoffrey Keir, Susana Barrio, and Edward J Thompson

Discrepancies between qualitative and quantitative analysis of cerebrospinal fluid IgG: densitometric comparison of nephelometry-silver versus immuno-enzymes
Ann Clin Biochem 45(4): 404-408; doi:10.1258/acb.2008.007056 [Abstract] [Full Text] [Figures Only] [PDF]  

Nicole Nagdyman, Peter Ewert, Katharina Schmitt, Michael Hübler, Brigitte Stiller, Christian Müller, and Felix Berger

Protein S-100 is present in extracerebral fluids before and after cardiac surgery in children
Ann Clin Biochem 45(4): 409-412; doi:10.1258/acb.2008.007251 [Abstract] [Full Text] [Figures Only] [PDF]  

Yoko Tabushi, Toyofumi Nakanishi, Tohru Takeuchi, Mikio Nakajima, Kazuhito Ueda, Takuya Kotani, Shigeki Makino, Akira Shimizu, Toshiaki Hanafusa, and Takayuki Takubo

Detection of citrullinated proteins in synovial fluids derived from patients with rheumatoid arthritis by proteomics-based analysis
Ann Clin Biochem 45(4): 413-417; doi:10.1258/acb.2007.007205 [Abstract] [Full Text] [Figures Only] [PDF]  

Taruna Likhari, T S Aulakh, Baldev M Singh, and R Gama

Does HbA_1C predict isolated impaired fasting glycaemia in the oral glucose tolerance test in subjects with impaired fasting glycaemia?
Ann Clin Biochem 45(4): 418-420; doi:10.1258/acb.2008.008017 [Abstract] [Full Text] [Figures Only] [PDF]  

David R Macdonald, Alison M Hanson, Martin R Holland, and Baldev M Singh

Clinical impact of variability in HbA_1c as assessed by simultaneously measuring fructosamine and use of error grid analysis
Ann Clin Biochem 45(4): 421-425; doi:10.1258/acb.2008.007259 [Abstract] [Full Text] [Figures Only] [PDF]  

Short Reports

Daniel Juan Herrera, Steven Moore, Sarah Heap, Mary Anne Preece, and Paul Griffiths

Can plasma ammonia be measured in patients with acute liver disease?
Ann Clin Biochem 45(4): 426-428; doi:10.1258/acb.2008.007175 [Abstract] [Full Text] [Figures Only] [PDF]  

M T Ackermans, L P Klieverik, E Endert, H P Sauerwein, A Kalsbeek, and E Fliers

Plasma insulin concentrations during a hyperinsulinaemic clamp: what do we measure?
Ann Clin Biochem 45(4): 429-430; doi:10.1258/acb.2008.007196 [Abstract] [Full Text] [PDF]  

Case Reports

Robert C Hawkins and Lian-King Lee

Immunoglobulin G paraprotein cross-reactivity with immunoglobulin M measurement
Ann Clin Biochem 45(4): 431-433; doi:10.1258/acb.2008.007236 [Abstract] [Full Text] [Figures Only] [PDF]  

Deborah L Bertfield, Odai Jumma, Robert D S Pitceathly, and Jon D Sussman

Copper deficiency: an unusual case of myelopathy with neuropathy
Ann Clin Biochem 45(4): 434-435; doi:10.1258/acb.2008.007218 [Abstract] [Full Text] [PDF]  

O C Maguire, D Mc Carthy, and S K Cunningham

The effect of plasmapheresis on the concentration of certain plasma proteins: a case identified by an inaccurate LDL-cholesterol estimation
Ann Clin Biochem 45(4): 436-439; doi:10.1258/acb.2008.007231 [Abstract] [Full Text] [PDF]  

Grainne O'Malley, Carla Moran, Mohd Shazlie Draman, Tom King, Diarmuid Smith, Chris J Thompson, and Amar Agha

Central pontine myelinolysis complicating treatment of the hyperglycaemic hyperosmolar state
Ann Clin Biochem 45(4): 440-443; doi:10.1258/acb.2008.007171 [Abstract] [Full Text] [Figures Only] [PDF]  

Letters

G P Mead, H D Carr-Smith, and A R Bradwell

Free light chains
Ann Clin Biochem 45(4): 444; doi:10.1258/acb.2008.072541 [Full Text] [PDF]  

Julia Forsyth and Peter Hill

Serum free light chains
Ann Clin Biochem 45(4): 444-445; doi:10.1258/acb.2008.008049 [Full Text] [PDF]  

Joanna Sheldon

Free light chains: author's response
Ann Clin Biochem 45(4): 445-446; doi:10.1258/acb.2008.072542 [Full Text] [PDF]  

Ann Bowron, Lisa Cooke, Jeff Scott, and Janet Stone

Paracetamol-induced 5-oxoprolinuira and high anion gap metabolic acidosis in a child on a ketogenic diet
Ann Clin Biochem 45(4): 446-447; doi:10.1258/acb.2008.008031 [Full Text] [PDF]  

E Chow, F Siddique, and R Gama

Thyrotoxicosis factitia: role of thyroglobulin
Ann Clin Biochem 45(4): 447-448; doi:10.1258/acb.2008.080611 [Full Text] [PDF]  

Jinny Jeffery and Ruth M Ayling

A simple method for excluding possible Citra-lock^TM contamination
Ann Clin Biochem 45(4): 448; doi:10.1258/acb.2008.008056 [Full Text] [PDF]  

Diarmuid Smith

Thyrotoxicosis factitia: author's response
Ann Clin Biochem 45(4): 448; doi:10.1258/acb.2008.080612 [Full Text] [PDF]  

End Pieces

   Journal Watch

Deepan Bathia

Ann Clin Biochem 45(4): 449; doi:10.1258/acb.2008.200817 [Full Text] [PDF]  

Paula Marchetti

Ann Clin Biochem 45(4): 449; doi:10.1258/acb.2008.200818 [Full Text] [PDF]  

   Piscator

Ann Clin Biochem 45(4): 450; doi:10.1258/acb.2008.200819 [Full Text] [PDF]  

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