Editorial

Anthony A Fryer and Fahmy W Hanna

Managing demand for pathology tests: financial imperative or duty of care?
Ann Clin Biochem 46(6): 435—437; first published on 12 October 2009 as doi: 10.1258/acb.2009.009186 [Full Text] [PDF]  

Personal View

W S A Smellie

Intravenous fluid therapy – an under-recognized patient safety opportunity
Ann Clin Biochem 46(6): 438—440; first published on 12 October 2009 as doi: 10.1258/acb.2009.009159 [Abstract] [Full Text] [PDF]  

Review Article

Jonathan G Middle and John W Kane

Oestradiol assays: fitness for purpose?
Ann Clin Biochem 46(6): 441—456; first published on 19 October 2009 as doi: 10.1258/acb.2009.009102 [Abstract] [Full Text] [Figures Only] [PDF]  

Original Articles

Masumi Ai, Akira Tanaka, Kentaro Shimokado, Rumiko Ohtani, Akihiro Inazu, Junji Kobayashi, Hiroshi Mabuchi, Takamitsu Nakano, and Katsuyuki Nakajima

A deficiency of cholesteryl ester transfer protein whose serum remnant-like particle-triglyceride significantly increased, but serum remnant-like particle-cholesterol did not after an oral fat load
Ann Clin Biochem 46(6): 457—463; first published on 29 July 2009 as doi: 10.1258/acb.2009.008249 [Abstract] [Full Text] [Figures Only] [PDF]  

D P Bathia, D R Carless, K Viswanathan, A S Hall, and J H Barth

Serum 99th centile values for two heart-type fatty acid binding protein assays
Ann Clin Biochem 46(6): 464—467; first published on 29 June 2009 as doi: 10.1258/acb.2009.009055 [Abstract] [Full Text] [Figures Only] [PDF]  

Mark Guy, Joanna K Borzomato, Ronald G Newall, Philip A Kalra, and Christopher P Price

Protein and albumin-to-creatinine ratios in random urines accurately predict 24 h protein and albumin loss in patients with kidney disease
Ann Clin Biochem 46(6): 468—476; first published on 3 September 2009 as doi: 10.1258/acb.2009.009001 [Abstract] [Full Text] [Figures Only] [PDF]  

Sandra D Mulder, Johannes A Heijst, Cees Mulder, Frans Martens, C Erik Hack, Philip Scheltens, Marinus A Blankenstein, and Robert Veerhuis

CSF levels of PSA and PSA–ACT complexes in Alzheimer's disease
Ann Clin Biochem 46(6): 477—483; first published on 3 September 2009 as doi: 10.1258/acb.2009.009130 [Abstract] [Full Text] [Figures Only] [PDF]  

R Sodi, L B Bailey, J Glaysher, L Allars, N B Roberts, E M Marks, and W D Fraser

Acidification and urine calcium: is it a preanalytical necessity?
Ann Clin Biochem 46(6): 484—487; first published on 3 September 2009 as doi: 10.1258/acb.2009.009027 [Abstract] [Full Text] [Figures Only] [PDF]  

Hagit Goldshtein, Michael J Hausmann, and Amos Douvdevani

A rapid direct fluorescent assay for cell-free DNA quantification in biological fluids
Ann Clin Biochem 46(6): 488—494; first published on 3 September 2009 as doi: 10.1258/acb.2009.009002 [Abstract] [Full Text] [Figures Only] [PDF]  

Qing-Ping Wang, Jian-Wen Gu, Xiang-Hong Zhan, Hui Li, and Xiang-Hang Luo

Assessment of glomerular filtration rate by serum cystatin C in patients undergoing coronary artery bypass grafting
Ann Clin Biochem 46(6): 495—500; first published on 3 September 2009 as doi: 10.1258/acb.2009.009065 [Abstract] [Full Text] [Figures Only] [PDF]  

Short Reports

N F Jassam, A Paterson, C Lippiatt, and J H Barth

Macroprolactin on the Advia Centaur: experience with 409 patients over a three-year period
Ann Clin Biochem 46(6): 501—504; first published on 22 October 2009 as doi: 10.1258/acb.2009.009059 [Abstract] [Full Text] [Figures Only] [PDF]  

Royce P Vincent, Frédérique E Etogo-Asse, Tracy Dew, William Bernal, Jamshid Alaghband-Zadeh, and Carel W le Roux

Serum total cortisol and free cortisol index give different information regarding the hypothalamus–pituitary–adrenal axis reserve in patients with liver impairment
Ann Clin Biochem 46(6): 505—507; first published on 2 September 2009 as doi: 10.1258/acb.2009.009030 [Abstract] [Full Text] [PDF]  

Tetsuo Ito, Shigekazu Yamamoto, Tsukasa Hayashi, Mika Kodera, Hiroaki Mizukami, Keiya Ozawa, and Shin-ichi Muramatsu

A convenient enzyme-linked immunosorbent assay for rapid screening of anti-adeno-associated virus neutralizing antibodies
Ann Clin Biochem 46(6): 508—510; first published on 3 September 2009 as doi: 10.1258/acb.2009.009077 [Abstract] [Full Text] [PDF]  

Marianne Wigger, Jan Schaible, Jutta Muscheites, Guenther Kundt, Dieter Haffner, and Dagmar-Christiane Fischer

Fetuin-A serum concentrations in healthy children
Ann Clin Biochem 46(6): 511—513; first published on 3 September 2009 as doi: 10.1258/acb.2009.009037 [Abstract] [Full Text] [Figures Only] [PDF]  

E Holmes, I Davies, G Lowe, and L R Ranganath

Circulating ghrelin exists in both lipoprotein bound and free forms
Ann Clin Biochem 46(6): 514—516; first published on 19 October 2009 as doi: 10.1258/acb.2009.008254 [Abstract] [Full Text] [Figures Only] [PDF]  

Graham Ross Dallas Jones

Critical difference calculations revised: inclusion of variation in standard deviation with analyte concentration
Ann Clin Biochem 46(6): 517—519; first published on 16 October 2009 as doi: 10.1258/acb.2009.009083 [Abstract] [Full Text] [Figures Only] [PDF]  

Case Reports

Karolina M Stepien, Rob Morris, Sandy Brown, Andrew Taylor, and Linda Morgan

Unintentional silver intoxication following self-medication: an unusual case of corticobasal degeneration
Ann Clin Biochem 46(6): 520—522; first published on 3 September 2009 as doi: 10.1258/acb.2009.009082 [Abstract] [Full Text] [PDF]  

Charmaine Cassar, Richard Procter, Fraser Davidson, Andrew Collier, Iqbal A Malik, Sujoy Ghosh, and Tarik A Elhadd

An unusual case of profound hyponatraemia and bilateral adrenal calcifications
Ann Clin Biochem 46(6): 523—526; first published on 1 October 2009 as doi: 10.1258/acb.2009.009078 [Abstract] [Full Text] [Figures Only] [PDF]  

P A H M Wijnen, I Limantoro, M Drent, O Bekers, P M J C Kuijpers, and G H Koek

Depressive effect of an antidepressant: therapeutic failure of venlafaxine in a case lacking CYP2D6 activity
Ann Clin Biochem 46(6): 527—530; first published on 12 October 2009 as doi: 10.1258/acb.2009.009003 [Abstract] [Full Text] [Figures Only] [PDF]  

Rebecca J Pattenden, Kerri L Davidson, and Philip R Wenham

The value of serum free light chains in a case of Waldenstrom's macroglobulinaemia that produces a type I cryoglobulinaemia
Ann Clin Biochem 46(6): 531—532; first published on 12 October 2009 as doi: 10.1258/acb.2009.009056 [Abstract] [Full Text] [Figures Only] [PDF]  

Letters

A P Courtney, P Holloway, and A Fairney

Stability of serum total N-terminal propeptide of type I collagen
Ann Clin Biochem 46(6): 533—534; first published on 12 October 2009 as doi: 10.1258/acb.2009.009093 [Full Text] [Figures Only] [PDF]  

Allan C Deacon

Interpretation of internal quality control: time for a re-think?
Ann Clin Biochem 46(6): 534—535; first published on 6 October 2009 as doi: 10.1258/acb.2009.009189 [Full Text] [Figures Only] [PDF]  

Books

Judith Fox

Applying Evidence-based Laboratory Medicine – A Step-by-step Guide
Ann Clin Biochem 46(6): 536; first published on 6 October 2009 as doi: 10.1258/acb.2009.200913 [Full Text] [PDF]  

William J Marshall

Biology of Disease
Ann Clin Biochem 46(6): 536—537; first published on 6 October 2009 as doi: 10.1258/acb.2009.200916 [Full Text] [PDF]  

Charles van Heyningen

Clinical Lipidology: A Companion to Braunwald's Heart Disease
Ann Clin Biochem 46(6): 537; first published on 6 October 2009 as doi: 10.1258/acb.2009.200917 [Full Text] [PDF]  

End Pieces

   Journal Watch

Heather Stoddart

Ann Clin Biochem 46(6): 538; first published on 12 October 2009 as doi: 10.1258/acb.2009.200914 [Full Text] [PDF]  

Karen Smith

Ann Clin Biochem 46(6): 538; first published on 12 October 2009 as doi: 10.1258/acb.2009.200915 [Full Text] [PDF]  

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