Capillary blood gas analysis in complex regional pain syndrome: a pilot study

Ann Clin Biochem 2003;40:569-571
doi:10.1258/000456303322326524
© 2003 Association for Clinical Biochemistry

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ECTH Tan,
MH de Keijzer and
RJA Goris


Department of General Surgery, University Medical Centre, Nijmegen, The Netherlands;
Department of Clinical Chemistry, University Medical Centre, Nijmegen, The Netherlands;
Department of General Surgery, University Medical Centre, Nijmegen, The Netherlands


Background: The pathophysiology of complex regional pain syndrometype 1 (CRPS 1) is still a matter of debate. An inflammatoryreaction may cause the syndrome. Increasing evidence pointsto a role for impairment of oxygen metabolism in the affectedlimb.

Methods: In this pilot study (16 patients) we performed capillary blood gas analysis in extremities with acute CRPS 1, in order to assess oxygen saturation and lactate concentrations. Comparison was made with the unaffected limb for capillary blood pH, pO2, SaO2, and lactate and glucose concentrations.

Results: No statistically significant differences could be found.

Conclusions: Capillary blood gas analysis is not useful to detectchanges in oxygen saturation and lactate concentrations in CRPS1.

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