Hypopituitarism presenting as a mixed hyperlipidaemia

Ann Clin Biochem 2004;41:344-345
© 2004 Royal Society of Medicine

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Case Report

Eric S Kilpatrick,
Jane E Patmore,
Christopher Rowland-Hill and
Stephen L Atkin

Department of Clinical Biochemistry, Hull Royal Infirmary, Hull HU3 2JZ, UK;
Department of Diabetes and Endocrinology, Hull Royal Infirmary, Hull HU3 2JZ, UK;
Department of Radiology, Hull Royal Infirmary, Hull HU3 2JZ, UK;
Department of Medicine, University of Hull, UK

A case report is presented of a 37-year-old man who, largelyby chance, was found to have a marked mixed hyperlipidaemia.As a teenager he had been treated for apparent idiopathic growthhormone deficiency, but had also never developed secondary sexualcharacteristics. Pituitary hormone measurement was now consistentwith hypopituitarism and magnetic resonance imaging showed hypoplasiaof his pituitary stalk as the likely cause. His hyperlipidaemiaimproved after appropriate hormone replacement. He thus appearsto have had a mixed hyperlipidaemia secondary to hypopituitarism,which was secondary to a pituitary stalk abnormality, whichin turn may have been associated to the trauma surrounding hisnormal breech delivery.

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