Evaluation of a card test for procalcitonin in continuous ambulatory peritoneal dialysis peritonitis

Ann Clin Biochem 2007;44:482-484
© 2007 Association for Clinical Biochemistry


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Fatma Meriç Yilmaz,
Gülsen Yilmaz,
Hatice Akay,
Murat Duranay and
Dogan Yücel

Clinical Biochemistry Laboratory, Ministery of Health, Ankara 06340, Turkey;
Dialysis Unit of Ankara Hospital, Ministery of Health, Ankara 06340, Turkey;
Clinical Biochemistry Laboratory, Ministery of Health, Ankara 06340, Turkey

Background: Peritonitis is an important complication in continuousambulatory peritoneal dialysis (CAPD) patients. Procalcitonin(PCT) has recently been identified as an inflammation markerand recommended as a new potential marker in CAPD peritonitis.We aimed to study a card test for PCT and compare the resultswith the conventional markers such as C-reactive protein (CRP),erythrocyte sedimentation rate (ESR) and white blood cell (WBC)count.

Patients and methods: A total of 40 CAPD patients; 20 patientswith an episode of peritonitis and 20 patients without any clinicalor laboratory sign of infection were included in the study.PCT, CRP, ESR, WBC and dialysate cell count were performed atthe beginning of the clinical signs of peritonitis.

Results: CRP and ESR had the highest sensitivities (100% forboth) but lower specificities (55 and 10%; respectively) andPCT had the highest specificity with a relatively low sensitivity(100 and 70%) according to the calculated results.

Conclusions: The card test for PCT seems to be suitable forthe adjunctional use in CAPD peritonitis, with its shorter turn-aroundtime, appropriateness for near-patient testing and high specificity.

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