Comparison of blood glucose meters in a New Zealand diabetes centre

This version was published on 1 July 2009

Ann Clin Biochem 2009;46:302-305
© 2009 Association for Clinical Biochemistry


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Original Articles

Christopher Florkowski1,2,
Christopher Budgen2,
Deborah Kendall1,
Helen Lunt1 and
M Peter Moore1

1 Diabetes Centre, Christchurch Hospital;
2 Canterbury Health Laboratories, PO Box 151, Christchurch, New Zealand

Corresponding author: Christopher Florkowski, Associate Professor, Canterbury Health Laboratories, PO Box 151, Christchurch, New Zealand. Email: Chris.Florkowski{at}

Background: To assess the accuracy and precision of the Roche Performa andMedisense Optium Xceed (5 and 10 s reading) blood glucose meters.

Methods: Capillary blood samples were taken from 100 patients attending a diabetes centre and blood glucose measured on Roche Performa (n = 4) and Medisense Optium Xceed 5 s (n = 2) and 10 s reading (n = 2) meters. Venous plasma glucose from samples taken simultaneously was measured by the laboratory hexokinase method as reference standard. Imprecision was determined on the meters by replicate analysis (n = 20) of control solutions provided by the manufacturersand also patient venous whole-blood samples. Accuracy was assessedrelative to the reference method by Bland–Altman plots,Passing and Bablok regression analysis, and both Clarke andconsensus error grid analysis. Coefficients of variation (CVs)were calculated to determine imprecision.

Results: Bland–Altman and Passing–Bablok analysis confirmedsignificant systematic bias for all meters, with relative under-readingof higher glucose concentrations. Error grid analysis showedthat <5% readings exceeded ±20% (or ±0.83 mmol/Lfor readings <4 mmol/L) deviation from the reference method(1%, 2% and 4% for the Roche, Optium 5 and 10 s meters, respectively).CVs were all <4% for the control solutions and <6% forpatient samples.

Conclusions: Both Roche Performa and Medisense Optium glucose meters (5 and10 s readings) perform satisfactorily and are acceptable foroperational use.

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